New Pill Could Help Men with Premature Ejaculation Last 4 Times Longer
Alternatively, researchers have been working on developing pharmaceutical pills to treat premature ejaculation, and one of them seems to be very promising, according to a new study from Tulane University School of Medicine.
The drug, called Cligosiban, is an oxytocin antagonist and works by preventing oxytocin, a.k.a. the love hormone, from binding to cells, thereby delaying orgasm.
In the six-week study, 88 participants with premature ejaculation were split into two groups and were given either a placebo or Cligosiban.
At the beginning of the study, the average time it took the men to orgasm was 33 seconds, and by the end of the trial, that had increased 3.8-fold for the participants who took the actual drug.
Considering the success of the study, the trial is currently being repeated at 29 centers across the U.S. with 220 participants.
A separate study on the effectiveness of Cligosiban published in the Journal of Sexual Medicine found that it’s “rapidly absorbed under fasting conditions with peak concentrations generally occurring within 1–2 hours post-dose,” meaning it works pretty fast and should be taken about an hour or two before sex for maximum benefits.
Scientists believe oxytocin antagonists are effective at delaying orgasm because the hormone is not only released after orgasm, but is a big part of arousal and triggers climaxes as well.
So, by blocking oxytocin from binding to cells, you can keep your orgasm at bay for a little while longer and it won’t sneak up on you before you’re ready for it.
However, with that being said, antagonizing the oxytocin receptor in the brain and spinal cord helps you last longer, but just might make your orgasms less intense in the process.
A German study published in the journal Hormones and Behavior revealed that people who used a nasal spray containing the hormone had more intense orgasms, which may mean that by doing the opposite and blocking the hormone, orgasms will be less mind-blowing.
While Cligosiban is still in the trial phase and not on the market just yet, it definitely seems promising, but more research is needed to determine any and all side effects and full uses.
But in the meantime, here are 10 heinous things to think about to hopefully buy yourself a few more precious minutes in bed.